Rabu, 12 Januari 2011

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This book provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations.

* Contributions from leading international authorities in the field
* Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system
* Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator

  • Sales Rank: #4014957 in eBooks
  • Published on: 2005-12-19
  • Released on: 2005-12-19
  • Format: Kindle eBook

From the Back Cover
Immunopotentiators in Modern Vaccines is an in-depth exploration of the current, most promising approaches to vaccine adjuvants. The book extends from examples of pre-clinical research all the way through to clinical evaluation, providing a thorough examination of the mechanisms which govern the activity of vaccine adjuvants and delivery systems. Wherever possible, a detailed description is provided to show how each adjuvant achieves its effects, highlighting opportunities for improving the design of adjuvants in the future.

Key Features:
* Immunopotentiators classified by function
* Exceptional illustrations depicting immunological pathways and the impact of adjuvants on cellular and molecular interactions
* US FDA perspectives highlight how future adjuvants will be approved for new generation vaccines

This book is intended for professionals and academics working in vaccinology who want up-to-date information about the mechanisms of modern immunopotentiators and their potential use in future rational vaccine design. It will also be an invaluable resource for decision makers and researchers in the field of vaccinology, policy makers, registration officers, marketing managers and students in the biomedical field.

Immunopotentiators in Modern Vaccines is edited by Virgil E.J.C. Schijns, (Professor, Dr, PhD) Head of Vaccine Technology and Immunology R&D Intervet Int. B.V. and Principal Immunologist, Nobilon Akzonobel, The Netherlands and part-time Professor in Immunology and Virology, Department of Population Health and Pathbiology, NC State University, Raleigh, USA; Derek T O’Hagan, (B.pharm, MR Pharm Soc GB, PhD) Senior Director and Head of Vaccine Delivery Research, Chiron Vaccines, Emeryville, USA.

About the Author
Dr. Virgil E.J.C. Schijns is special guest Professor in Cell Biology & Immunology group, Wageningen University, 6708 WD Wageningen, The Netherlands. Dr. Schijns received his Ph.D. degree at Utrecht University in 1990. Recent professional appointments are Chief Scientific Officer at ERC in Belgium and The Netherlands, (2011 to present); Chief Technology Officer, Vice-president at a small biotech spin-off from Utrecht University (2008 to 2011); Special professor immune Intervention, Wageningen University and Research center (2008 to present); Special Professor in Immunology and Virology at North Carolina State University (NCSU), Raleigh. Department of Population Health and Pathobiology (2002 to present) and Head of Department for Vaccine Technology and Immunology (VTI), AKZO NOBEL (1999 to 2008).

Dr. Derek O’Hagan was the Global Head of Vaccine Chemistry and Formulation Research for Novartis Vaccines, based in Cambridge, MA until acquisition by GSK in March, 2015. He managed research teams (~50 total staff) in Cambridge and Siena, Italy. He originally qualified as a pharmacist in the UK, and is a former academic researcher who has worked on vaccine delivery in the industry since 1993. He was formerly a Lecturer in Drug Delivery at the Department of Pharmaceutical Sciences, University of Nottingham, UK, and received research funding from the World Health Organization, The Wellcome Trust and the Medical Research Council. He was recruited into the US in 1993, and moved to progress basic research into clinical evaluation, then subsequently worked on several vaccine delivery systems that were evaluated in the clinic, including novel adjuvants, nucleic acid vaccines and needle free vaccines. In the mid 1990’s, Dr. O’Hagan worked on the emulsion adjuvant MF59, which is now included in a licensed flu vaccine in more than 40 countries and is progressing towards licensure in the US. He has co-authored >140 original research publications, >60 book chapters and reviews and I am a named inventor on >60 filed patents. He was awarded the Conference Science medal of the Royal Pharmaceutical Society of Great Britain in 1997, and the Young Investigator Research Achievement Award of the Controlled Release Society in 1999. He was also named as the ‘most inventive scientist’ in Chiron in 2004 and was the lead author on the most cited paper in ‘Vaccine’ 2008-10. Dr. O’Hagan served on the Board of Scientific Advisors for the Controlled Release Society and is a Fellow of the American Association of Pharmaceutical Scientists.

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Selasa, 11 Januari 2011

[G302.Ebook] Free PDF Skill Building Journal: Caring for Preschool Children, by Teaching Strategies, Derry G. Koralek, Diane Trister Dodge

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  • Sales Rank: #1081802 in Books
  • Brand: Brand: Delmar Pub
  • Published on: 2004-01-01
  • Original language: English
  • Number of items: 1
  • Dimensions: .80" h x 8.56" w x 10.94" l, 2.15 pounds
  • Binding: Paperback
  • 250 pages
Features
  • Used Book in Good Condition

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Senin, 10 Januari 2011

[M911.Ebook] PDF Ebook Veron: Corals of Australia and the Indo-Pacific

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  • Published on: 1609
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Minggu, 09 Januari 2011

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Excerpt from Mining and Mine Ventilation: A Practical Handbook on the Physics

In adding to the number of text-books on Mine Ventilation the author aims to provide new material and to dwell more fully on the fundamental theories and laws of ventilation, and to furnish, if possible, to the student a more suggestive method of study in a more graphic form.

While ventilation experts practically agree upon the essential theorems in ventilation, it is believed, however, that the subject may yet hold a new attractiveness and be more readily mastered if a few important principles, which are now generally misunderstood by the student, are magnified.

The method of determining the size of fan, etc., to ventilate a mine under given conditions, together with certain facts pertaining to the water gauge, and the chapter on Mine Fires are entirely new features.

The author wishes to express his gratitude to the Robinson Ventilating Co. of Pittsburgh, Pa.; The American Blower Company, and their manager, Thomas W. Fitch, Jr., Detroit, Mich.; The Jeffrey Manufacturing Co., Columbus, Ohio; The Colliery Engineer, Scranton, Pa.; M. B. King, Expert Assistant in Industrial Education, Harrisburg, Pa.; and The Taylor Instrument Co., Rochester, N. Y., for many illustrations, tables and other information used in this book.

About the Publisher

Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com

This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

  • Sales Rank: #6936289 in Books
  • Published on: 2015-09-27
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.02" h x .46" w x 5.98" l, .66 pounds
  • Binding: Paperback
  • 218 pages

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Selasa, 28 Desember 2010

[G113.Ebook] PDF Ebook Novum Testamentum Graece: Nestle-Aland 28th EditionFrom German Bible Society

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This is the twenty-eighth edition of the Nestle-Aland Novum Testamentum Graece (NA28). NA28 is the standard scholarly edition of the Greek New Testament used by scholars, Bible translators, professors, students, and pastors worldwide. Now NA28 has been revised and improved:• Critical apparatus revised and easier to use• Papyrii 117-127 included for the first time• In-depth revision of the Catholic Epistles, with more than 30 changes to the upper text• Scripture references systematically reviewed for accuracyThis large print edition also has generous margins for note-taking, making it an ideal study tool for pastors and students.

  • Sales Rank: #730341 in Books
  • Color: Blue
  • Published on: 2013-05-01
  • Format: Large Print
  • Original language: Greek
  • Number of items: 1
  • Dimensions: 9.40" h x 1.30" w x 6.60" l, 2.45 pounds
  • Binding: Hardcover
  • 824 pages

About the Author
The Institute for New Testament Textual Research is located at the University of Munster. Their central task is to research the textual history of the New Testament and to reconstruct its Greek initial text on the basis of the entire manuscript tradition, the early translations and patristic citations. Foremost among the results of this research is the ongoing publication of the Editio Critica Maior. The Institute produces several more editions and a variety of tools for NT scholarship, including the concise editions known as the "Nestle-Aland Novum Testamentum Graece" and the "UBS Greek New Testament."

Most helpful customer reviews

6 of 6 people found the following review helpful.
An excellent addition to, but not a replacement of, the NA27
By RJY
This is an excellent edition. I prefer the large print edition as the text is easily readable and the apparatus is clear. The standard size has an apparatus that, in many cases, is almost unreadable without a lens.

Don't discard the NA27, however. There are enough changes, exclusions, in the apparatus of the 28th that you will absolutely need the 27th to maintain continuity.

2 of 2 people found the following review helpful.
Should you 'upgrade' your Nestle-Aland 27?
By Amazon Customer
(This is about the text, not the large print edition offered here.)

This is exactly what Nestle-Aland users have come to expect from previous editions.

If you have a previous edition, should you "upgrade"? Yes, but only if you must have the latest and greatest, or if you are seriously working with textual criticism in the Catholic Epistles, or if your professor requires it. Otherwise, it may not be worth the money

For those not familiar with NA 28, two changes are noteworthy.

First, the critical apparatus has been somewhat revised (probably not very important for most users).

Second, the text has changed in a tiny way and in a monumental way. Tiny, because only a handful of changes have been made, and these in the Catholic Epistles (thus, for perhaps 99% of Nestle-Aland users there is no substantial reason to update your NA 27). Monumental, in that in the Catholic Epistles the eclectic textual method of all previous editions has been abandoned for the new approach used in the Editio Critica Maior (of which only the Catholic Epistles have been published so far), namely a method called the Coherence-Based Geneological Method (CBGM). Of course this is of concern only to those interested in textual criticism.

For most, including most pastors, the most useful Greek New Testament is probably the UBS text, 4th edition (whose text is identical to Nestle-Aland 27), or the new UBS 5 (minor text adjustments to match Nestle-Aland 28), which will serve you well for decades.

The difference between the Nestle-Aland text and the United Bible Society's text? The texts themselves are identical, except for minor punctuation variations. The important differences are in the apparati underneath the text. The NA apparatus is concerned with variations among the manuscripts (but not all mss. evidence is presented - that would be far too voluminous for a single volume of this size), while the UBS apparatus is concerned with a subset of textual evidence: that which would make a difference in translating the text (most variations in the mss. simply do not affect translation). For students, of course, you will buy the text your professors require; for others, you should consider the above or, if you can get your hands on both, appearance might be the deciding factor.

All in all a beautiful production, the result of painstaking work by generations of scholars to whom we owe a great debt.

One additional note: these texts are based on more than a century of scientific study of textual criticism, which teaches, among other things, that all things being equal, the oldest manuscripts are probably the closest to the autographs (the original writings). Scientific study of all manuscripts has resulted in this NA28/UBS5 text, which thus may be closer to the autographs than any single manuscript.

A completely different point of view concerning the correct set of methods needed to get as close to the autographs as possible has risen in the last few decades. This method maintains that the majority of the manuscripts (which, naturally are the youngest ones, as the older ones are more likely to have worn out or otherwise gotten destroyed) represents the most accurate text type, and if you want to get close to the words of the autographs, you should rather trust what the majority says, rather than the oldest manuscripts. The resultant text is called the Majority Text and is represented in print by another set of Greek New Testaments than the two discussed here (they are also available on Amazon). Their prefaces present convincing prima face arguments as to the superiority of their approach. Unfortunately, unless you are well informed as to the principles of both points of view, you probably are not qualified to judge these issues - that is the nature of a good prima facie argument. (Since I believe in the scientific approach of the Nestle-Aland tradition, I cannot present a strong defense of the Majority Text textual critical principles here.)

At any rate, the differences between these two textual critical approaches do not in the end produce results that differ greatly.
Perhaps a good way to explain the differences in the two traditions is to compare the textual differences between the King James Version (which more or less translates the Majority Text) and most modern translations (which conform generally to the Nestle-Aland text).

0 of 0 people found the following review helpful.
excellent critical apparatus
By roberto daniel
what changes is the critical apparatus , being large font is easy to visualize the different variants

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Novum Testamentum Graece: Nestle-Aland 28th EditionFrom German Bible Society PDF
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Novum Testamentum Graece: Nestle-Aland 28th EditionFrom German Bible Society PDF

Novum Testamentum Graece: Nestle-Aland 28th EditionFrom German Bible Society PDF
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Senin, 27 Desember 2010

[J709.Ebook] Free Ebook Is There A God Volume 1: Why Do Some People Not Believe in God? (Is there A God?), by Leslie Buckland Jnr

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Is There A God Volume 1: Why Do Some People Not Believe in God? (Is there A God?), by Leslie Buckland Jnr

“Is there a God?” is a series of five books that challenges believers and non-believers to consider carefully developed arguments with strong supporting evidence in addressing the age-old issues related to whether God is a myth or fact.

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Volume 1 deals with the question as to why some people do not believe in God. His analysis is as intriguing as it is revealing.

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  • Sales Rank: #1161095 in eBooks
  • Published on: 2011-12-26
  • Released on: 2011-12-26
  • Format: Kindle eBook

Most helpful customer reviews

0 of 1 people found the following review helpful.
Very Good
By CRiley
Brother Buckland presented Gods Word accurately and thought provoking will share them in Bible class and encourage other Brothers and Sisters to purchase his books.

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Selasa, 21 Desember 2010

[Q706.Ebook] Download Ebook Business: Its Legal, Ethical, and Global Environment, by Marianne M. Jennings

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Business: Its Legal, Ethical, and Global Environment, by Marianne M. Jennings

Offering the best preparation for future managers, BUSINESS: ITS LEGAL, ETHICAL, & GLOBAL ENVIRONMENT, 8e, teaches you how to understand and apply legal and ethical concepts to real business. Going further than simply introducing you to the legal environment, this text offers the most comprehensive and integrated approach to exploring the intersection of law, business strategy, and ethics. It provides thorough coverage of relevant legal issues in the context of practical business examples--and includes almost 300 real-world applications! Almost every page illustrates the clear relevance of chapter concepts to issues you will face in the real world. Intriguing cases and critical-thinking exercises motivate you to apply law and ethics to real business scenarios.

  • Sales Rank: #1120443 in Books
  • Published on: 2008-01-09
  • Original language: English
  • Number of items: 1
  • Dimensions: 1.34" h x 8.45" w x 10.19" l, 3.95 pounds
  • Binding: Hardcover
  • 896 pages

About the Author
Marianne M. Jennings, Emeritus Professor of Legal and Ethical Studies, has taught at the WP Carey School of Business, Arizona State University from 1977 through the present. She has six textbooks and four monographs in circulation in the areas of business ethics, ethical culture, and legal environment. She was director of the Lincoln Center for Applied Ethics from 1995 to 1999. Professor Jennings has worked with government agencies, professional organizations, colleges and universities, and Fortune 100 companies on ethics training and culture. She is a contributing editor of Corporate Finance Review and Real Estate Law Journal. Two of her books have been named Library Journal's book of the year. Her books have been translated into three languages. Her book, The Seven Signs of Ethical Collapse, was published by St Martin's Press and has been used as both an audit tool and a primer by numerous organizations for creating and sustaining an ethical culture. In 2011, Professor Jennings was named one of the Top 100 Thought Leaders by Trust Across America and in 2012 she was named one of the 100 most influential people in business ethics by Ethisphere magazine. Professor Jennings served on the board of directors for Arizona Public Service (now Pinnacle West), the owner of the Palo Verde Nuclear Station, from 1987 through 2000. She has also served on INPO's advisory council since 2005. She conducts ethics training and ethical culture assessments for businesses, including Fortune 100 companies, government agencies, professional associations, and nonprofit organizations.

Most helpful customer reviews

0 of 0 people found the following review helpful.
Not exactly 'like new'
By On the way to MBA
Having purchased only new books previously, I was hesitant to purchase a 'used' book, but had reviewed many positive comments relative to the quality of the used books received. Knowing that my used texts from college are in practically new condition, I went for the 50% savings over the cost of a new text with a used book described as 'like new'.

The book arrived within the allotted timeframe, but appeared to have a pot of coffee spilled on it. The entire bottom corner of the book (about 1 to 2 inches in) is discolored and in some cases, pages are sticking together. Although I'm over halfway through the text, only two notes have been identified so far, so the inside of the book was essentially untouched other than the staining.

It still reads, so is serving its purpose. I was a little disappointed to have a stained book, but it was nothing that required returning or hasn't fulfilled the requirement. I was hoping for a used book with good notes from the last user, but apparently received a spilled coffee over some late night cramming? I'll probably go back to new for future classes.

0 of 0 people found the following review helpful.
So interesting, I wrote the author
By K. York
Now, really. Just look at that title. Could a book be more b-o-r-i-n-g?? Boy! was I wrong. You will be amazed at all the cases Jennings packs in this book right along with newbie instruction. And you will find yourself reading WAY past what you looked up in the index. It's that interesting.

I'm keeping this one in my professional library (and my husband has even used it as reference in his degree program) and even wrote to the author telling her so. I definitely wasn't expecting humor in a "law book," but that's what I found. If this is a textbook for a class (as it was for me), you're in for an interesting few weeks of reading.

0 of 0 people found the following review helpful.
Outstanding Business Resource
By Zachary G. Madrigal
This book was used in my MBA Business Law course and was so well designed I purchased this text as my business law reference book. The book itself is an excellent resource not only for my business law class but have used in other MBA courses I have taken. The text is written in a simple and easy to understand format. The 8th edition is the most current edition and covers all business legal matters. A must have reference resource! Overall, I recommend this book.

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